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Chronic Leukemias (Overview)

Dipl.-Ing. (FH) Tanja Hinrichsen

Chronic leukemias are characterized by a slow progression, which frequently remains unnoticed over a longer period of time. The leukemia cells are more mature in the chronic form than in acute leukemia, which means that malignant transformation takes place in a later stage of the development process. Depending on the affected cell line, there is a distinction between chronic lymphocytic leukemia (CLL) and chronic myeloid leukemia (CML). While CLL belongs to the indolent B-cell lymphomas, CML belongs to the group of myeloproliferative neoplasms (MPN).

Both conditions are characterized in more detail by cytological/histological, cytochemical, immunological, cytogenetic and molecular genetic methods in order to give a prognosis.